Supports Heart Health
Palm oil is enriched in vitamin E in the form of alpha-, gamma-, and delta-tocotrienols. Dietary tocotrienol supplements have been shown to prevent atherosclerosis development in patients and preclinical animal models. However, the mechanistic basis for this health beneficial effect is not well established. Read more
Fengjuan Li, Wenjuan Tan, Zhanfang Kang, Chi-Wai Wong
Publications: AtherosclerosisDate: Jan 2010
Tocotrienols are natural farnesylated analogues of tocopherols which decrease hepatic cholesterol production and reduce plasma cholesterol levels in animals. Read more
R A Parker, B C Pearce, R W Clark, D A Gordon, J J Wright
Publications: Journal of Biological ChemistryDate: May 1993
Tocotrienols have been reported to improve lipid profiles, reduce atherosclerotic lesions, decrease blood glucose and glycated haemoglobin concentrations, normalise blood pressure in vivo and inhibit adipogenesis in vitro, yet their role in the metabolic syndrome has not been investigated. Read more
Weng-Yew Wong, Hemant Poudyal, Leigh C. Ward, Lindsay Brown
Publications: NutrientsDate: Oct 2012
Ageing is a nonmodifiable risk factor that is linked to increased likelihood of cardiovascular morbidities. Whilst many pharmacological interventions currently exist to treat many of these disorders such as statins for hypercholesterolemia or beta-blockers for hypertension, the elderly appear to present a greater likelihood of suffering non-related side effects such as increased risk of developing new onset type 2 diabetes (NODM). Read more
Nardev Ramanathan, Esther Tan, Li Jun Loh, Boon Seng Soh, Wei Ney Yap
Publications: Nutrition & MetabolismDate: Jan 2018
This review emphasizes the effects of tocotrienols on the risk factors for atherosclerosis, plaque instability and thrombogenesis, and compares these effects with tocopherol. Tocotrienols reduce serum lipids and raise serum HDL-C. Alpha-tocopherol, on the other hand, has no effect on serum lipids. Tocotrienols have greater antioxidant activity than tocopherols. Both reduce the serum levels of C-reactive protein (CRP) and advanced glycation end products, and expression of cell adhesion molecules. The CRP-lowering effects of tocotrienols are greater than tocopherol. Read more
Kailash Prasad
Publications: Current Pharmaceutical DesignDate: 2011
